Job Description Nemours Children's Health - Delaware Swank Autism Center Wilmington, DE The Swank Autism Center at Nemours Children's Health is seeking a Research Scientist (open rank) to join our team. The Swank Autism Center provides comprehensive clinical services for children up to age 21 years and conducts research and community-based outreach and training. We are seeking applicants with demonstrable training and experience working in clinical and/or research settings with autistic/neurodivergent children, adolescents, and/or young adults, and their families. The Research Scientist will develop a targeted research program in autism. Current research studies or immediate potential opportunities are available in examining inequities and disparities in healthcare delivery, progressive assessment models, hospital-wide autism initiatives, adolescence/postsecondary transition, and other areas. The Research Scientist will also provide some clinical services as a part of this role, which might include autism diagnostic services, individual/group therapy, and supervising trainees in working with patients and families from the larger Delaware Valley community. This position will have joint appointments in the Swank Autism Center and the Center for Healthcare Delivery Science - Delaware Valley (www.nemours.org/chds). The CHDS is a research center across the Nemours enterprise. Anne E. Kazak, Ph.D., ABPP is the enterprise director, Melissa A. Alderfer, PhD is the Center Director in Delaware and Susana Patton, PhD is the Center Director in Florida. The CHDS includes 20+ investigators that study ways to improve health care, health equity, and health and wellness beyond medicine for youth and their families. Research projects span a variety of medical conditions (e.g., diabetes, cancer, cardiac conditions, obesity, sickle cell disease, cystic fibrosis, pain) and other health-related challenges (COVID-19 vaccine hesitancy, homelessness, maternal post-partum depression, racism). The research scientist will join a multidisciplinary team including providers in psychology, developmental medicine, psychiatry, neurology, social work, nursing, and applied behavior analysis, as well as colleagues who are autistic and/or caregivers. The Swank Autism Center has a dedicated Clinical Research Coordinator and CHDS has additional research coordination and data analysis resources. Equity, diversity, and inclusion guide our growth and strategy. We are looking for individuals who are passionate about, and committed to, leading efforts to provide culturally relevant, neuro-affirming care, promoting anti-ableist mental health care, reducing health disparities, and helping build a diverse and inclusive team environment. Autistic/neurodivergent applicants are welcomed. The Research Scientist would have opportunities to precept trainees including externs, residents, and/or fellows who rotate through the center. Teaching, training, and mentoring are core values in our division and these efforts are supported and encouraged. We are committed to expanding pathways that promote a diverse workforce and as such, are intentional in our hiring and retention practices. We practice continuous learning through awareness-enhancing and bias-reduction educational opportunities that guide our overarching lens of health equity. Faculty are encouraged to participate in the Division of Behavioral Health's active and energetic Diversity Committee. Minimum Qualifications Education <ul> <li>Candidates must hold a PhD, MD, MD/PhD, or other doctoral degree in a health-related discipline and demonstrate evidence of collaborative academic productivity and either success in obtaining funding for research or a strong potential to obtain funding for research.</li></ul> APPLICATION: Please send a letter of interest and CV to WLMBH-DMRecruitment@Nemours.org and please state "Autism Research Scientist" in the subject line. Applications currently are being reviewed and will be accepted until the position is filled. About Nemours: As one of the nation's leading pediatric health care systems, Nemours is committed to providing all children with their best chance to grow up healthy. We offer integrated, family-centered care to more than 300,000 children each year in our pediatric hospitals, specialty clinics, primary care practices, and school-based health centers in Delaware, Florida, Maryland, New Jersey and Pennsylvania. Nemours strives to ensure a healthier tomorrow for all children - even those who may never enter our doors - through our world-changing research, education, and advocacy efforts. At Nemours, our Associates help us deliver on the promise we make to every family we have the privilege of serving: to treat their child as if they were our own. Psychologists are members of the medical staff at Nemours Children's Hospital, Delaware and are supported with applying for an academic appointment through the Sidney Kimmel Medical College at Thomas Jefferson University. Nemours (Nemours.org) is an open and welcoming place to work, and values diversity in all its forms. Additionally, Nemours aspires to have its workforce and providers reflect the rich diversity of the communities we serve. Candidates of diverse backgrounds, Spanish-speaking applicants, and those committed to working with diverse populations and conversant in multicultural values are strongly encouraged to apply. Associates are encouraged to join Associate Resource Groups as members or allies to support colleagues of diverse identities and lived experiences. About Us As one of the nation's premier pediatric health care systems, we've made a promise to do whatever it takes to prevent and treat even the most disabling childhood conditions. It's a promise that extends beyond our nationally recognized clinical treatment to an entire integrated spectrum of research, advocacy, education, and prevention. Equity, diversity, and inclusion guide our growth and strategy. We are looking for individuals who are passionate about, and committed to, leading efforts to provide culturally relevant care, reducing health disparities, and helping build a diverse and inclusive environment. All Nemours Associates are expected to ensure that these philosophies are embedded in their day-to-day work with colleagues, patients and families. Nemours aspires to have its workforce and providers reflect the rich diversity of the communities we serve. Candidates of diverse backgrounds, race and ethnicity, religion, age, gender, sexual orientation, and those committed to working with diverse populations and conversant in multicultural values are strongly encouraged to apply. Please click here to review Nemours Anti-Racism Statement (nemours.org). To learn more about Nemours and our commitment to treat every child as if they were our own, visit us at www.nemours.org.

Research Scientist, In Vitro Cell Culture - Contract - Wilmington, DEProclinical is currently working alongside a pharmaceutical company seeking a Research Scientist specializing in In Vitro Cell Culture to join their team.Primary Responsibilities:<ul><li>Conduct routine cell culture procedures, including cell line maintenance, expansion, and cryopreservation.</li><li>Perform routine laboratory tasks, including reagent preparation, equipment maintenance, and supply management.</li><li>Collaborate with team members on large-scale cell preparation for high throughput screening.</li><li>Perform DMPK/ADME assays including Caco-2 permeability, PAMPA, protein binding, drug transporter assays, etc.</li><li>With appropriate supervision, analyze data, record data, prepare summary documents, and report data as needed.</li><li>Timely, accurate and compliant entry of experimental data into Electronic Laboratory Notebook (ELN).</li></ul>Minimum Requirements:<ul><li>Bachelor's degree in a relevant scientific discipline with over 4 years of experience or an M.S. with over 2 years (industry experience preferred).</li><li>Strong preference given to candidates with a demonstrated ability to work using aseptic cell culture techniques.</li><li>Independently manage tasks and assignments as directed by immediate supervisor.</li><li>High-throughput screening and LC/MS/MS experience preferred.</li><li>Attention to detail, and effective oral and written communication skills.</li></ul>
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Director of Clinical Research Scientist - Contract - Wilmington, DEProclinical is recruiting for an experienced and dedicated Director to head up the Clinical Research team.Primary Responsibilities:This role will work closely with physicians within Clinical Development to support clinical research programs. The successful candidate will be required to focus on developing protocols, contributing to program strategies, and drafting clinical scientific documents. This position requires a proactive approach to data review and collaboration with various stakeholders.Skills & Requirements:<ul><li>Degree in a scientific or life-sciences field; Pharm.D. or Ph.D. preferred.</li><li>Minimum of 8 years of experience in research with at least 5 years of drug development experience are required. Alternative drug development experience will be considered.</li><li>Ability to work independently and manage multiple tasks in a fast-paced environment.</li><li>Excellent written and oral communication skills.</li><li>Strong analytical abilities.</li><li>Willingness to travel up to 20% as needed.</li></ul>The Director of Clinical Research Scientist's responsibilities will be:<ul><li>Develop protocols for clinical studies.</li><li>Contribute to program strategy development for assigned compounds/programs.</li><li>Draft and review clinical scientific documents such as INDs, Investigator Brochures, and Health Authority submissions.</li><li>Provide clinical input into eCRF design, SAP, and TLFs.</li><li>Collaborate with study team members to review study data and identify trends.</li><li>Represent clinical development on project teams.</li><li>Develop relationships with consultants and external experts for protocol feedback.</li><li>Lead the creation of study abstracts, posters, presentations, and manuscripts.</li><li>Serve as a liaison to project teams, CROs, and clinical sub-teams.</li><li>Maintain updated knowledge of the competitive landscape and evolving standards of care.</li></ul>
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OverviewIncyte is a biopharmaceutical company focused on the discovery, development, and commercialization of novel medicines to meet serious unmet medical needs in oncology and inflammation and autoimmunity. Incyte is committed to the rigorous pursuit of research and development excellence to improve the lives of patients, make a difference in health care, and build sustainable value.The Company strives to discover and develop first-in-class and best-in-class medicines-advancing a diverse portfolio of large and small molecules.<h3>Job Summary (Primary function)</h3>The Sr Research Scientist, DMB is responsible for the DMPK support of discovery and/or development projects and may include conducting in vitro ADME assays, biotransformation, transporter work, bioanalytical method validation, and bioanalysis of study samples utilizing LC-MS/MS.<h3>Essential Functions of the Job (Key responsibilities)</h3><ul><li>Conduct routine cell culture procedures, including cell line maintenance, expansion, plating and cryopreservation.</li><li>Perform routine laboratory tasks, including reagent preparation, analytical standard preparation, routine equipment maintenance, and supply management.</li><li>Collaborate with team members on large-scale cell preparation and maintenance for high throughput screening studies.</li><li>Perform DMPK/ADME in vitro assays including cell-based permeability (e.g. Caco-2), PAMPA, protein binding, substrate and inhibition drug transporter assays, etc. The cell-based assays are supporting both high throughput screening and more definitive/detailed studies meant to support kinetic and drug-drug interaction analyses.</li><li>Must have excellent sterile laboratory technique and be capable of establishing and maintaining long term cell cultures, including those of human origin.</li><li>With appropriate training must be able to independently analyze data, record data, prepare summary documents, and report data (written and oral) as needed.</li><li>Timely, accurate and compliant entry of experimental data into Electronic Laboratory Notebook (ELN).</li><li>Perform LC-MS/MS quantitation of samples in a setting of discovery bioanalysis. This may include method development, validation, and conducting sample analysis.</li><li>Perform laboratory experiments with radioactive compounds in a safe and compliant manner.</li><li>Knowledge of applicable regulatory guidelines and appropriate SOP trainings.</li><li>Write/contribute to reports for regulatory filings as needed.</li><li>Provide training to other scientists as required.</li></ul><h3>Qualifications (Minimal acceptable level of education, work experience, and competency)</h3>* BS/MS degree in Life Sciences or equivalent experience.* DMPK knowledge and experience in the biopharmaceutical or life sciences industry.Disclaimer: The above statements are intended to describe the general nature and level of work performed by employees assigned to this job. They are not intended to be an exhaustive list of all duties, responsibilities, and qualifications. Management reserves the right to change or modify such duties as required.Incyte Corporation is committed to creating a diverse environment and is proud to be an equal opportunity employer.
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With recent significant expansion in our research portfolios, particularly related to research on pediatric health equity, The Center for Healthcare Delivery Science (CHDS) at Nemours Children's Health is pleased to announce the availability of a new faculty position for a mid or senior career faculty member. This position is based in Delaware and is attached to our newly funded Research Expanding Access to Child Health (REACH) Center , funded by an NIH Centers of Biomedical Research Excellence (COBRE) grant (1P20GM144270). The goals of the REACH Center are to provide the mentorship and infrastructure to launch and sustain programs of research focused on using stakeholder engaged methods to develop, evaluate, and implement technology-enhanced interventions to reduce inequities in child health.The ideal candidate will hold an MD, MD/PhD, PhD or other doctoral degree in a health-related discipline and demonstrate evidence of collaborative academic productivity and prior success in obtaining funding for healthcare delivery science research. We invite applications from qualified researchers in any pertinent discipline. Areas of emphasis for the position include, but are not limited to, health equity, implementation science, technology- enhanced interventions, intervention science, and health economics. A portion of this position can be dedicated to clinical service in the candidate's professional specialty if desired. Nemours research scientists typically have faculty appointments in the Department of Pediatrics of Sidney Kimmel Medical College at Thomas Jefferson University.The CHDS ( <a href="#">https://www.nemours.org/pediatric-research/area/health-care-delivery-science.html</a> ) is a research center across the Nemours enterprise. Anne E. Kazak, Ph.D., ABPP is the enterprise director, Melissa A. Alderfer, Ph.D. is the Center Director in Delaware and Susana R. Patton, Ph.D., ABPP is the Center Director in Florida. Our 17 investigators study ways to improve health care, health equity, education, and health and wellness beyond medicine for youth and their families. Research projects span a variety of topics, including resilience, experiences of adversity (e.g., housing instability, post-partum depression, racism, caregiver loss, maltreatment) including specific medical conditions (diabetes, cancer, cardiac conditions, obesity, sickle cell disease, cystic fibrosis, chronic pain), transition to adult healthcare, and other resources and challenges (early care and education, COVID-19 vaccine hesitancy, environmental justice, cardiovascular risks) in child health. We have a dedicated biostatistician, data analysts, and an inhouse group of clinical research coordinators to support studies. Nemours is also a member of PEDSNet, providing access to electronic health record data, and other databases. Salary and benefits are highly competitive.All inquiries will be treated confidentially. Interested applicants should submit a curriculum vitae and cover letter Dana Berger, MPH, Program Administrator ( <a href="#">Dana.Berger@nemours.org</a> )
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<div>
Overview:
Incyte is a biopharmaceutical company focused on the discovery, development, and commercialization of novel medicines to meet serious unmet medical needs in oncology and inflammation and autoimmunity. Incyte is committed to the rigorous pursuit of research and development excellence to improve the lives of patients, make a difference in health care, and build sustainable value.
The Company strives to discover and develop first-in-class and best-in-class medicines-advancing a diverse portfolio of large and small molecules.
<h3>Research Scientist / Sr. Research Scientist, Cell Line Development</h3>
Job Summary
The Research Scientist/Senior Research Scientist in Cell Line Development will be responsible for the development of commercially viable cell lines that will be used in the production of therapeutic recombinant proteins such as fusion protein, monoclonal and bispecific antibodies.
Essential Functions of the Job (Key responsibilities)
<ul>
<li>Execute experiments to support cell line development, including linearizing plasmid DNA, transfecting CHO cells, routine cell passaging and maintenance, and secure freezing.</li>
<li>Execute transfection and selection of transfected cell lines.</li>
<li>Design and conduct high throughput assays to screen mAb or BsAb clones, ensuring production, product quality, and genetic stability of cell lines.</li>
<li>Operate Ambr 15 Fed-batch study to evaluate pools and clones.</li>
<li>Ensure clone monoclonality meets regulatory expectations.</li>
<li>Create and maintain research cell banks.</li>
<li>Oversee Master and Working Cell Banks manufactured and tested at Contract Labs.</li>
<li>Manage laboratory supplies and instrument maintenance.</li>
<li>Participate and present updates in routine group meetings.</li>
<li>Ensure all work is appropriately documented in electronic lab notebook and reports are written in a timely manner.</li>
</ul>
Minimum Requirements
<ul>
<li>Bachelor’s degree with 2-4 years of hands-on experience in cell culture for biologics; or Master’s degree with 1-3 years of experience in molecular or cell biology, chemical engineering, or a related field.</li>
<li>Prefer at least 2 years’ experience in CHO cell culture work; aseptic techniques are required.</li>
<li>Experience in CHO cell culture and transfection.</li>
<li>Experience with high throughput techniques in 384 and/or 96 well plate format such as: Octet, ELISA, Guava, ProA Spin-Column purification.</li>
<li>Experience with automated liquid handler is a plus.</li>
<li>Experience with statistical Design of Experiment is a plus.</li>
<li>Effective planning skills; ability to anticipate resource needs and help establish priorities.</li>
<li>Ability to develop effective, flexible relationships with others; understands the business agendas and perspectives of others; recognizes and effectively balances the interests and needs within the organization.</li>
</ul>
</div>
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Research Scientist, In Vitro Cell Culture - Contract - Wilmington, DEProclinical is currently working alongside a pharmaceutical company seeking a Research Scientist specializing in In Vitro Cell Culture to join their team. Primary Responsibilities:The successful candidate will be responsible for conducting routine cell culture procedures, collaborating on large-scale cell preparation, and performing various DMPK/ADME assays, with a requirement for timely and accurate data entry into an Electronic Laboratory Notebook (ELN). Minimum Requirements:<ul><li>Bachelor's degree in a relevant scientific discipline with over 4 years of experience or an M.S. with over 2 years (industry experience preferred).</li><li>Strong preference given to candidates with a demonstrated ability to work using aseptic cell culture techniques.</li><li>Independently manage tasks and assignments as directed by immediate supervisor.</li><li>High-throughput screening and LC/MS/MS experience preferred.</li><li>Attention to detail, and effective oral and written communication skills.</li></ul> The Research Scientist, In Vitro Cell Culture's responsibilities will be:<ul><li>Conduct routine cell culture procedures, including cell line maintenance, expansion, and cryopreservation.</li><li>Perform routine laboratory tasks, including reagent preparation, equipment maintenance, and supply management.</li><li>Collaborate with team members on large-scale cell preparation for high throughput screening.</li><li>Perform DMPK/ADME assays including Caco-2 permeability, PAMPA, protein binding, drug transporter assays, etc.</li><li>With appropriate supervision, analyze data, record data, prepare summary documents, and report data as needed.</li><li>Timely, accurate and compliant entry of experimental data into Electronic Laboratory Notebook (ELN)</li></ul> If you are having difficulty in applying or if you have any questions, please contact Mike Raletz at m.raletz@proclinical.com Proclinical is a specialist employment agency and recruitment business, providing job opportunities within major pharmaceutical, biopharmaceutical, biotechnology and medical device companies.Proclinical Staffing is an equal opportunity employer.

Research Scientist Jobs in Wilmington, DE

Research Scientist Autism
December 14, 2024

Research Scientist In Vitro Cell Culture
December 11, 2024

Director Clinical Research Scientist
December 11, 2024

Sr Research Scientist Dmb
December 9, 2024

Senior Research Scientist
December 8, 2024

Research Scientist Sr Research Scientist Cell Line Development
December 8, 2024

Research Scientist In Vitro Cell Culture
November 28, 2024

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Research Scientist Jobs in Wilmington, DE

Research Scientist AutismDecember 14, 2024

Research Scientist In Vitro Cell CultureDecember 11, 2024

Director Clinical Research ScientistDecember 11, 2024

Sr Research Scientist DmbDecember 9, 2024

Senior Research ScientistDecember 8, 2024

Research Scientist Sr Research Scientist Cell Line DevelopmentDecember 8, 2024

Research Scientist In Vitro Cell CultureNovember 28, 2024