Job Description: OUR TEAM: Our Tailored R&D Solutions (TRS) business leverages Promega's innovative technologies and R&D expertise to provide customized solutions and a strategic partnership to help advance clients' drug discovery and development workflows. TRS screening services support client drug discovery ventures through high-throughput screening (HTS) and compound selectivity profiling. We are a dynamic, and highly collaborative team that is focused on delivering high quality data with rigor, reproducibility, an operations mindset and a relentless pursuit of excellence. YOUR ROLE: As a Research Scientist in our TRS screening services team, you will play a pivotal role in executing all lab operations. You will design, validate, and screen client compound against our innovative suite of cellular assays using our state-of-the-art laboratory automation. You will work with program management to ensure timely completion of customer projects. You will work closely with the broader R&D organization to transfer new assays and technologies into our screening services portfolio. This position offers a challenging and rewarding opportunity to directly contribute to our clients projects, the growth of the business and to the success of our team. TRS screening services is a rapidly growing business within Promega with significant career development and growth opportunities. YOUR EXPERIENCE: You have a strong laboratory background in cell biology, including mammalian cell culture. You have a strong commitment to constant process improvement and optimization. You have experience in some or all of the following areas: cell culture, laboratory automation, method development and validation, compound management, HTS and or selectivity profiling, laboratory informatics, data analysis and scientific writing. Prior experience working in a fee-for-service or CRO setting is highly desired. CORE DUTIES: 1. Responsible for the execution, analysis, and delivery of compound screening and profiling projects for clients. Designs, executes, analyzes and troubleshoots screening runs. Takes initiatives to achieve project outcomes. 2. Develops and executes robust compound management capabilities that ensures compound availability, integrity and traceability. 3. Design and implement laboratory automation methods. 4. Ensures smooth transition and scalability during assay and technology transfer from R&D into the TRS screening services. 5. Drives process improvement initiatives that grow the capabilities, capacity, and robustness of the lab in order to better support our customers and grow the business. 6. Delivers high-quality, accurate data via rigorous and reproducible automation workflows. 7. Provides clear, insightful data reports and engages effectively with clients to interpret results, offering expert advice and recommendations. 8. Fosters strong relationships with clients and internal teams to ensure project objectives are met in a timely and efficient manner. 9. Stays up-to-date on relevant industry technologies, methodologies, and trends, and implement new techniques or lab automation as necessary. KEY QUALIFICATIONS: 1. B.S. degree in scientific discipline with 3-9 years post graduate lab experience. 2. Demonstrated competence in the design and execution of complex experimental strategies. PHYSICAL DEMANDS: 1. Ability to work at lab bench or laminar flow hood for extended period of time. 2. Ability to wear personal protective equipment while in the lab (gloves, lab coat, safety glasses, etc.). 3. Ability to operate a computer. At Promega, we value diversity and strive to create an inclusive workplace. We are proud to be an Equal Opportunity Employer, making employment decisions without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, veteran status, disability, or any other protected class.

JOB OBJECTIVE: Promega is a global leader in providing innovative solutions and technical support to life scientists in academic, industrial and government settings.Join our team at Promega and play a pivotal role in developing cutting-edge recombinant enzymes for protein and nucleic acid analytical applications, as well as therapeutic production processes. This exciting position calls for a deep understanding of biochemistry, enzymology, enzyme optimization via mutagenesis, protein purification, and analytical methods including UV-RP-HPLC, LC/MS, and qPCR. We seek a dynamic candidate with the versatility to effortlessly transition between diverse projects and objectives, consistently delivering high-quality data to drive enzyme application advancements. Proficiency in bioinformatic tools is essential, with a strong preference for expertise in synthetic biology and AI-driven computational approaches for enzyme structural modifications. Excellent communication skills, both written and oral, are vital for internal presentations and customer interactions. As a collaborative member of our multidisciplinary team, you will also lead the writing of scientific publications, patents, and other professional communications. Additionally, you will have the opportunity to influence decisions for future developments, shaping the direction of innovative biotechnological advancements. Join us and be a part of a team that's making a real impact in the field of biotechnology.CORE DUTIES:1. Designing and optimizing expression and purification of recombinant enzymes.2. Development of enzymological assays.3. Leveraging advanced AI tools to optimize enzyme design and predict functional properties, thus accelerating the development process and enhancing or modifying the enzyme performance characteristics. This work requires expertise in enzyme mutagenesis.4. Lead product development. This activity includes formulation of product development strategy to meet project milestones and timeline, creating and executing experimental plan and maintaining the project documentation.5. Support post-launch commercialization activities including writing technical materials and publishing peer-reviewed papers.6. Contribute to preparation of patents.7. Present the products at scientific and industry meetings.8. Maintain communication with customers and KOLs to define critical product requirements and ensure adequate product testing. Collaborate with customers on characterization of the developed products and co-publish the obtained results. Conduct customer visits.9. Provide customer support including handling customers' inquiries and assisting Technical Services.10. Monitor trends in protein and nucleic acid analytical field and therapeutic production processes. Identify opportunities for novel enzyme development in these fields.11. Demonstrates inclusion through their own words and actions and is accountable for a safe workspace. Acts with kindness, curiosity and respect for others.12. Embracing and being open to incorporating Promega's 6 Emotional & Social Intelligence (ESI) core principles in daily work.13. Understand and comply with all elements of the Promega Quality System outlined for the position.KEY QUALIFICATIONS:1. Successful candidates should have a PhD degree in a scientific discipline with 0-3 years post graduate experience.2. Prior work in industry is a plus.PREFERRED QUALIFICATIONS:1. Proven expertise in expression of recombinant proteins in microbial cultures.2. Proven expertise in designing and optimizing protein purification.3. Broad expertise in protein and nucleic acid analytical techniques including SDS-PAGE analysis, Western blot hybridization, RP HPLC, PCR and others. Prior work with LC-MS is a plus.4. Proven expertise in enzyme characterization and development of enzymological assays.5. Knowledge of bioinformatic tools. Experience with AI-driven computational tools and proven use of these tools to advance research objectives is highly desirable.6. Proven problem-solving skills.7. Proven presentation and interpersonal communication skills. A candidate is expected to conduct expert-level discussions with customers about analytical and production enzymes and identify unmet customers' needs in these products.PHYSICAL DEMANDS:1. Ability to work at lab bench or fume hood for extended period of time2. Ability to wear protection gear (gloves, lab coat, safety glasses, etc.)3. Ability to operate a computerAt Promega, we value diversity and strive to create an inclusive workplace. We are proud to be an Equal Opportunity Employer, making employment decisions without regard to race, color, religion, sex, sexual orientation, gender identity, ational origin, veteran status, disability, or any other protected class.

Research Scientist Jobs in Madison, WI

Research Scientist
November 13, 2024

Sr Research Scientist 1 Enzyme Development
November 11, 2024

Statistical Research Scientist Machine Learning
November 4, 2024

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Research Scientist Jobs in Madison, WI

Research ScientistNovember 13, 2024

Sr Research Scientist 1 Enzyme DevelopmentNovember 11, 2024

Statistical Research Scientist Machine LearningNovember 4, 2024

Quick filters

Top companies

Research Scientist
November 13, 2024

Sr Research Scientist 1 Enzyme Development
November 11, 2024

Statistical Research Scientist Machine Learning
November 4, 2024