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10X Genomics Interview Questions

10X Genomics Interview Guides

Let’s say that your company is running a standard control and variant AB test on a feature to increase conversion rates on the landing page. The PM checks the results and finds a .04 p-value.

How would you assess the validity of the result?

Experiment Validity

You are testing hundreds of hypotheses with many t-tests. What considerations should be made?

What is a key disadvantage of the F-test when compared to multiple t-tests?

What is a key disadvantage of the F-test when compared to multiple t-tests?

Hundreds of Hypotheses

You are testing hundreds of hypotheses with many t-tests. What considerations should be made?

In an A/B test, how can you check if assignment to the various buckets was truly random?

In an A/B test, which of the following is a common method to determine if the assignment to the test groups was truly random?

In an A/B test, which of the following is a common method to determine if the assignment to the test groups was truly random?

Random Bucketing

10X Genomics Salaries by Position

About the Role: At 10x Genomics, everything we do is driven by our mission: To accelerate the mastery of biology to advance human health. Our Marketing Strategy & Insights function is a cross-disciplinary team that plays a key role in developing insights on market opportunities and strategies for success. We build tools and frameworks to help make informed, data-driven decisions. We are committed to hiring the world's best and brightest people with knowledge and skill sets at the intersection of market research, marketing operations, data analytics, and data science. What you will be doing: This role will work cross-functionally to build the framework, underlying data structures, tools, and processes for measuring the effectiveness of our marketing and drive continuous improvement. The successful candidate will be responsible for providing data-driven insights such as building business cases, data modeling, and performance reporting. Initial responsibilities will include, but are not limited to: <ul> <li>Increase actionable insights and improve decision-making across the company by:</li> <ul> <li>Contributing data science expertise to market research and market modeling efforts</li> <li>Support Marketing teams by developing campaign attribution models to identify high impact campaigns</li> <li>Supporting Product Management teams in building business cases for new product concepts</li> <li>Leading internal marketing efforts to determine master data requirements and align across functions and systems to enable more efficient and robust reporting</li> <li>Improving underlying processes and data structures for reporting</li> <li>Identifying high impact channels and recommending the optimized channel mix</li> </ul> <li>Drive continuous improvement in our marketing by:</li> <ul> <li>Partnering with Marketing Analytics and Finance to define CAC and LTV, and building a framework to implement in reporting</li> <li>Implementing A/B test frameworks and educating stakeholders across marketing to increase adoption</li> <li>Modeling marketing mix and suggesting next best action on a personalized basis</li> <li>Improving reporting tools that serve both executives and execution-oriented marketers</li> </ul> </ul> Minimum Requirements: <ul> <li>BS in STEM or related field</li> <li>Minimum 3 years’ experience in a related role</li> <li>Strong analytical skills</li> <li>Advanced knowledge of R, SQL, Python (e.g., pandas, jupyter notebooks) for data manipulation</li> <li>Applied statistics and machine learning experience (regression analysis, time series, probabilistic models, supervised and unsupervised methods)Deep understanding of data architecture, pipelines, and enterprise systems</li> <li>Experience with effective data visualization and reporting tools (i.e. Tableau, PowerBI) and open-source Python libraries (i.e. Plotly and Bokeh)</li> <li>Proven ability to turn data analysis into actionable business insights and recommendations with quick turnaround times</li> <li>Excellent problem-solving, project management, and communication skills.</li> <li>Ability to interpret complex information and provide strategic recommendations in a simple and concise manner.</li> <li>Demonstrated ability to work independently and manage multiple priorities in a fast paced environment.</li> </ul> Preferred Qualifications: <ul> <li>Experience with marketing operations and analytics for a multinational company as specified in “About the Role” (data structures for marketing systems, marketing mix, survey analysis)</li> <li>Experience with Python application development frameworks (Flask, Django) and data app frameworks (Streamlit)</li> <li>Experience using Generative AI models and frameworks e.g., ChatGPT, open source LLM, Langchain, Retrieval Augmented Generation (RAG)</li> <li>Understanding of businesses financials and ability to articulate work in terms of contribution to financials and mission</li> <li>BS/MBA in Finance, Accounting, Economics, Business Analytics (preferred both)</li> </ul> Below is the base pay range for this full time position. The actual base pay will depend on several factors unique to each candidate, including one’s skills, qualifications, and experience. At 10x, base pay is also just one component of the Company’s total compensation package. This role is also eligible for 10x’s equity grants, its comprehensive health and retirement benefit programs, and its annual bonus program or sales incentive program. Your 10x recruiter can share more about the Company’s total compensation package during the hiring process. Pay Range $143,000 — $193,000 USD About 10x Genomics At 10x Genomics, accelerating our understanding of biology is more than a mission for us. It is a commitment. This is the century of biology, and the breakthroughs we make now have the potential to change the world. We enable scientists to advance their research, allowing them to address scientific questions they did not even know they could ask. Our tools have enabled fundamental discoveries across biology including cancer, immunology, and neuroscience. Our teams are empowered and encouraged to follow their passions, pursue new ideas, and perform at their best in an inclusive and dynamic environment. We know that behind every scientific breakthrough, there is a deep infrastructure of talented people driving the life sciences industry and making it possible for scientists and clinicians to make new strides. We are dedicated to finding the very best person for every aspect of our work because the innovations and discoveries that we enable together will lead to better technologies, better treatments, and a better future. Find out how you can make a 10x difference. Individuals seeking employment at 10x Genomics are considered without regards to race, color, religion, national origin, age, sex, marital status, ancestry, physical or mental disability, veteran status, gender identity, or sexual orientation,or any other characteristic protected by applicable law. 10x does not accept unsolicited applicants submitted by third-party recruiters or agencies. Any resume or application submitted to 10x without a vendor agreement in place will be considered unsolicited and property of 10x, and 10x will not pay a placement fee.
#J-18808-Ljbffr

About the role10x Genomics was founded to deliver powerful and reliable tools that fuel key scientific discoveries and drive exponential progress in our mastery of biology to advance human health. Our talented team has a distinguished record of creating innovative instruments, reagents, and software that analyze biological systems at a resolution that matches the complexity of biology.We are looking for a Staff Software Engineer to join our Instrument Software team.You have expert-level knowledge of creating advanced instrument control software with C, C++, Python and/or Rust. You handle asyncio, threading, multiprocessing and interfacing with low-level drivers, firmware & hardware with ease. You understand the power and flexibility Python brings, but also its limitations. You are a stickler for testing and thrive on creating a clean and maintainable codebase.You are the engineer that other engineers can count on; you are technically excellent, you attack every problem with enthusiasm, you care deeply about what it takes to build high quality software. You are a self-starter, team player, have the hunger to venture quickly into unknown areas, code and make the system work.What you will be doingHands-on coding of Python and C++ based control systems for our instrumentsArchitecture and system design of next generation instrumentsLong-term evolution of our instrument codebaseMentoring of team membersMinimum requirementsBachelor's degree in computer science, engineering, math, or scientific discipline with 8 years experience; OR Master's degree with 6 years of experience in software developmentExperience leading software team(s) in a technical capacityInstrumentation system design & architectureModern C++Embedded DevelopmentPython3LinuxPreferred skills and experienceControl Systems DevelopmentFirmware Development & EE knowledge (Digital & Analog Design)Rapid software prototyping & validation with attention to detail and engineering diligenceStrong analytical and problem-solving skillsStrong verbal and written communication skillsBackground in biology and DNA sequencing is not required. Interest in the field is.#LI-RT1#LI-OnsiteBelow is the base pay range for this full time position. The actual base pay will depend on several factors unique to each candidate, including one's skills, qualifications, and experience. At 10x, base pay is also just one component of the Company's total compensation package. This role is also eligible for 10x's equity grants, its comprehensive health and retirement benefit programs, and its annual bonus program or sales incentive program. Your 10x recruiter can share more about the Company's total compensation package during the hiring process.Pay Range $203,000 $275,000 USD About 10x GenomicsAt 10x Genomics, accelerating our understanding of biology is more than a mission for us. It is a commitment. This is the century of biology, and the breakthroughs we make now have the potential to change the world.We enable scientists to advance their research, allowing them to address scientific questions they did not even know they could ask. Our tools have enabled fundamental discoveries across biology including cancer, immunology, and neuroscience.Our teams are empowered and encouraged to follow their passions, pursue new ideas, and perform at their best in an inclusive and dynamic environment. We know that behind every scientific breakthrough, there is a deep infrastructure of talented people driving the life sciences industry and making it possible for scientists and clinicians to make new strides. We are dedicated to finding the very best person for every aspect of our work because the innovations and discoveries that we enable together will lead to better technologies, better treatments, and a better future. Find out how you can make a 10x difference.Individuals seeking employment at 10x Genomics are considered without regards to race, color, religion, national origin, age, sex, marital status, ancestry, physical or mental disability, veteran status, gender identity, or sexual orientation,or any other characteristic protected by applicable law.10x does not accept unsolicited applicants submitted by third-party recruiters or agencies. Any resume or application submitted to 10x without a vendor agreement in place will be considered unsolicited and property of 10x, and 10x will not pay a placement fee.#J-18808-Ljbffr

10x Genomics was founded to deliver powerful and reliable tools that fuel key scientific discoveries and drive exponential progress in our mastery of biology to advance human health. Our talented team has a distinguished record of creating innovative instruments, reagents, and software that analyze biological systems at a resolution that matches the complexity of biology. As a Full Stack Software Engineer, you will routinely interact with computational biologists, scientists, infrastructure teams, other development teams, and our manufacturing teams. Your work will involve creating software services, tooling, and infrastructure, as well as building application frameworks and templates for other developers, automating quality control processes, and creating apps that track vital experimental information. In addition, your work will allow software engineers across the company to more effectively develop, test, and ship highly robust and performant software. These will primarily be React applications on top of AWS services. In addition, you will be building backend services in AWS to support various 10x products and services. As 10x's product lines mature and evolve, you will be exposed to a variety of new technologies and asked to develop new tools and services to support our cutting-edge R&D efforts by engaging across the company with other teams. What you will be doing Design, build, test, and ship production-ready software. Work with scientists, hardware, product management, and other software teams to determine the shape of new features and services to build. Dive deeply into your users technical challenges and assist them with efficient solutions. Provide strong technical leadership and a focus on continuous improvement. Develop systems for efficiently managing petabytes of genomic and image data. Build and maintain software processes, tools, and infrastructure. Make substantive changes to existing internal web tools across the stack, from cloud deployment to UI changes. Develop single-page React applications as well as service APIs to serve and display experimental data. Deploy and monitor internal applications. Minimum Requirements Bachelor's degree in computer science, engineering, math, or scientific discipline and 6 years of software development experience; OR 8 years of professional experience building software. Significant programming experience and expertise with Python. Significant programming experience and expertise with Javascript for front-end development. Preferred skills and experience Proficiency with Go and React. Excellent understanding of computer science fundamentals. Expertise with Linux, Docker, and Kubernetes. Development experience with TypeScript. Experience testing and deploying applications either to the cloud or within a production manufacturing environment. Deep understanding of testing, build, continuous integration, deployment & continuous monitoring. Experience designing long-term data storage in a variety of stores, and the knowledge to know what storage schemes are best for different kinds of data. Demonstrated disciplined and rigorous software engineering practices You understand the importance of software processes in service of engineering You understand the importance of testing Willingness to solve problems irrespective of where it is in the tech stack. A background in biology is not required, but curiosity and scientific interest is. LI-RW1 LI-Remote Below is the U.S. base pay range for this full-time position. The actual base pay will depend on several factors unique to each candidate, including one's skills, qualifications, experience, and location. At 10x, base pay is also just one component of the Company's total compensation package. This role is also eligible for 10x's equity grants, its comprehensive health and retirement benefit programs, and its annual bonus program or sales incentive program. Your 10x recruiter can share more about the specific base pay range for your preferred location, as well as the Company's total compensation package, during the hiring process. Pay Range $183,000$275,000 USD About 10x Genomics At 10x Genomics, accelerating our understanding of biology is more than a mission for us. It is a commitment. This is the century of biology, and the breakthroughs we make now have the potential to change the world. We enable scientists to advance their research, allowing them to address scientific questions they did not even know they could ask. Our tools have enabled fundamental discoveries across biology including cancer, immunology, and neuroscience. Our teams are empowered and encouraged to follow their passions, pursue new ideas, and perform at their best in an inclusive and dynamic environment. We know that behind every scientific breakthrough, there is a deep infrastructure of talented people driving the life sciences industry and making it possible for scientists and clinicians to make new strides. We are dedicated to finding the very best person for every aspect of our work because the innovations and discoveries that we enable together will lead to better technologies, better treatments, and a better future. Find out how you can make a 10x difference. Individuals seeking employment at 10x Genomics are considered without regards to race, color, religion, national origin, age, sex, marital status, ancestry, physical or mental disability, veteran status, gender identity, or sexual orientation,or any other characteristic protected by applicable law. 10x does not accept unsolicited applicants submitted by third-party recruiters or agencies. Any resume or application submitted to 10x without a vendor agreement in place will be considered unsolicited and property of 10x, and 10x will not pay a placement fee.

About the role 10x Genomics was founded to deliver powerful and reliable tools that fuel key scientific discoveries and drive exponential progress in our mastery of biology to advance human health. Our talented team has a distinguished record of creating innovative instruments, reagents, and software that analyze biological systems at a resolution that matches the complexity of biology. We are looking for a Senior Software Engineer to join our Instrument Software team. You have expert-level knowledge of creating advanced instrument control software & firmware with C, C++, Python and/or Rust. You can handle threading, multiprocessing, and interfacing with low-level drivers, firmware & hardware with ease. You are a stickler for testing and thrive on creating a clean and maintainable codebase. You are the engineer that other engineers can count on; you are technically excellent, you attack every problem with enthusiasm, you care deeply about what it takes to build high-quality software. You are a self-starter, team player, have the hunger to venture quickly into unknown areas, code, and make the system work. You will be working closely with fluidics, electrical, mechanical, optical, and fellow embedded software engineers (and the occasional biologist) to put together functioning prototypes that allow us to quickly test new designs and theories, as well as contributing to production systems. Ideal candidates will be independent operators that enjoy working in a lab with physical components and have a deep understanding of real-time asynchronous systems. Applicants must love tinkering and have a true hacker mindset. What you will be doing Designing and developing embedded control software and firmware for cutting-edge biological instrumentation platforms Working with electrical engineers to develop functional drivers and appropriate control schemes and interfaces Negotiating/determining prototype requirements with design engineers from partner teams (e.g. Mechanical Engineering, Optical Engineering, Electrical Engineering) Designing and implementing automated test scripts built on top of your control software Contributing to the entire software lifecycle from requirements gathering to validation Writing well-structured, testable, efficient, and maintainable software Writing software to control hardware prototypes Writing drivers and low-level hardware control software Developing application-level business logic (e.g. dispense, measure, aspirate) Developing small but interactive engineering GUIs For example: given hardware you have never used, quickly write a python interface to control it Minimum requirements Bachelor's degree in computer science, engineering, math, or scientific discipline with 5 years of experience; OR Masters degree with 3 years of experience in software development Embedded/Firmware Development Modern C++ Python3 Linux Preferred skills and experience Grasp of the basics of classical control theory and experience implementing control algorithms (e.g. PID, lead-lag, MPC) Exposure to digital signals processing (DSP) such as simple signal conditioning (e.g. IIR/FIR low pass filtering) Confident usage of Python scientific and numerical computing and visualization packages (e.g. numpy, pandas, matplotlib) EE knowledge (Digital & Analog Design) and familiarity with laboratory test equipment (e.g. digital multimeter, oscilloscope, signal analyzer, etc.) Rapid software prototyping & validation with attention to detail and engineering diligence Strong analytical and problem-solving skills Strong verbal and written communication skills Formal approach to design & architecture of complex instruments/systems Background in biology and DNA sequencing is not required. Interest in the field is. J-18808-Ljbffr

About the role We are looking for an exceptional Software Engineer to build out our growing cloud infrastructure and HPC platform with a solid understanding of Linux, cloud, and distributed computing to join our team. Our multi-disciplinary team in microfluidics, biochemistry, mechanical engineering, computational biology, and software has a proven track record of delivering successful commercial products built on deep technological innovation. If you are a self-starter who is passionate about building and operating reliable, scalable and performant systems, and is excited to work in a highly collaborative environment alongside a diverse team of experts every day, join us at 10x Genomics. This is a hybrid role in Pleasanton, CA. What you will be doing Design, build, deploy, and maintain resilient and scalable services and High Performance Computing (HPC) systems in the cloud. Scale systems and improve operational efficiency through extensive automation. Collaborate with the software engineering team on continuous delivery and deployment. Monitor infrastructure and applications for uptime and resource utilization, identify performance bottlenecks, troubleshoot and mitigate system issues, and develop solutions to improve reliability and performance. Maintain detailed documentation of system build and operational procedures. Participate in on-call rotations. Minimum Requirements Bachelor's degree in Computer Science or a related field, or equivalent work experience. 5 years software engineering experience in Python or Go. 3 years Linux systems engineering and operational experience. Experience with AWS services and infrastructure. Experience with Infrastructure as Code (ex. Terraform, Ansible), CI/CD tools/systems. Preferred Skills and Experience Proficiency in shell scripting and at least one other language, e.g. Python or Go. Ability to dive into unfamiliar code bases to troubleshoot and resolve issues. Previous experience with container based solutions like Docker. Experience with Kubernetes (installation, configuration, and troubleshooting). Knowledge of Linux kernel tuning, networking, and performance optimization. Experience with deployment management tools like ArgoCD. Experience in managing multi-petabyte scale network-attached storage (NAS) and operational knowledge of the NFS protocol. Strong desire to learn and implement new technologies. Excellent written and verbal communication skills. LI-RW1 LI-Onsite Below is the base pay range for this full time position. The actual base pay will depend on several factors unique to each candidate, including one's skills, qualifications, and experience. At 10x, base pay is also just one component of the Company's total compensation package. This role is also eligible for 10x's equity grants, its comprehensive health and retirement benefit programs, and its annual bonus program or sales incentive program. Your 10x recruiter can share more about the Company's total compensation package during the hiring process. Pay Range $177,000$239,000 USD About 10x Genomics At 10x Genomics, accelerating our understanding of biology is more than a mission for us. It is a commitment. This is the century of biology, and the breakthroughs we make now have the potential to change the world. We enable scientists to advance their research, allowing them to address scientific questions they did not even know they could ask. Our tools have enabled fundamental discoveries across biology including cancer, immunology, and neuroscience. Our teams are empowered and encouraged to follow their passions, pursue new ideas, and perform at their best in an inclusive and dynamic environment. We know that behind every scientific breakthrough, there is a deep infrastructure of talented people driving the life sciences industry and making it possible for scientists and clinicians to make new strides. We are dedicated to finding the very best person for every aspect of our work because the innovations and discoveries that we enable together will lead to better technologies, better treatments, and a better future. Find out how you can make a 10x difference. Individuals seeking employment at 10x Genomics are considered without regards to race, color, religion, national origin, age, sex, marital status, ancestry, physical or mental disability, veteran status, gender identity, or sexual orientation,or any other characteristic protected by applicable law. 10x does not accept unsolicited applicants submitted by third-party recruiters or agencies. Any resume or application submitted to 10x without a vendor agreement in place will be considered unsolicited and property of 10x, and 10x will not pay a placement fee.

About the role 10x Genomics was founded to deliver powerful and reliable tools that fuel key scientific discoveries and drive exponential progress in our mastery of biology to advance human health. Our talented team has a distinguished record of creating innovative instruments, reagents, and software that analyze biological systems at a resolution that matches the complexity of biology. We are looking for a Senior Software Engineer to join our Instrument Software team. You have expert-level knowledge of creating advanced instrument control software & firmware with C, C++, Python and/or Rust. You can handle threading, multiprocessing, and interfacing with low-level drivers, firmware & hardware with ease. You are a stickler for testing and thrive on creating a clean and maintainable codebase. You are the engineer that other engineers can count on; you are technically excellent, you attack every problem with enthusiasm, you care deeply about what it takes to build high-quality software. You are a self-starter, team player, have the hunger to venture quickly into unknown areas, code, and make the system work. You will be working closely with fluidics, electrical, mechanical, optical, and fellow embedded software engineers (and the occasional biologist) to put together functioning prototypes that allow us to quickly test new designs and theories, as well as contributing to production systems. Ideal candidates will be independent operators that enjoy working in a lab with physical components and have a deep understanding of real-time asynchronous systems. Applicants must love tinkering and have a true hacker mindset. What you will be doing <ul> <li>Designing and developing embedded control software and firmware for cutting-edge biological instrumentation platforms </li> <li>Working with electrical engineers to develop functional drivers and appropriate control schemes and interfaces </li> <li>Negotiating/determining prototype requirements with design engineers from partner teams (e.g. Mechanical Engineering, Optical Engineering, Electrical Engineering) </li> <li>Designing and implementing automated test scripts built on top of your control software </li> <li>Contributing to the entire software lifecycle from requirements gathering to validation </li> <li>Writing well-structured, testable, efficient, and maintainable software </li> <li>Writing software to control hardware prototypes </li> <ul> <li>Writing drivers and low-level hardware control software </li> <li>Developing application-level business logic (e.g. dispense, measure, aspirate) </li> <li>Developing small but interactive engineering GUIs </li> <li>For example: given hardware you have never used, quickly write a python interface to control it </li> </ul> </ul> Minimum requirements <ul> <li>Bachelor's degree in computer science, engineering, math, or scientific discipline with 5 years of experience; OR Master’s degree with 3 years of experience in software development </li> <li>Embedded/Firmware Development </li> <li>Modern C++ </li> <li>Python3 </li> <li>Linux </li> </ul> Preferred skills and experience <ul> <li>Grasp of the basics of classical control theory and experience implementing control algorithms (e.g. PID, lead-lag, MPC) </li> <li>Exposure to digital signals processing (DSP) such as simple signal conditioning (e.g. IIR/FIR low pass filtering) </li> <li>Confident usage of Python scientific and numerical computing and visualization packages (e.g. numpy, pandas, matplotlib) </li> <li>EE knowledge (Digital & Analog Design) and familiarity with laboratory test equipment (e.g. digital multimeter, oscilloscope, signal analyzer, etc.) </li> <li>Rapid software prototyping & validation with attention to detail and engineering diligence </li> <li>Strong analytical and problem-solving skills </li> <li>Strong verbal and written communication skills </li> <li>Formal approach to design & architecture of complex instruments/systems </li> <li>Background in biology and DNA sequencing is not required. Interest in the field is. </li> </ul>#J-18808-Ljbffr

About the role 10x Genomics was founded to deliver powerful and reliable tools that fuel key scientific discoveries and drive exponential progress in our mastery of biology to advance human health. Our talented team has a distinguished record of creating innovative instruments, reagents, and software that analyze biological systems at a resolution that matches the complexity of biology. We are looking for a Staff Software Engineer to join our Instrument Software team. You have expert-level knowledge of creating advanced instrument control software with C, C++, Python and/or Rust. You handle asyncio, threading, multiprocessing and interfacing with low-level drivers, firmware & hardware with ease. You understand the power and flexibility Python brings, but also its limitations. You are a stickler for testing and thrive on creating a clean and maintainable codebase. You are the engineer that other engineers can count on; you are technically excellent, you attack every problem with enthusiasm, you care deeply about what it takes to build high quality software. You are a self-starter, team player, have the hunger to venture quickly into unknown areas, code and make the system work. What you will be doing <ul> <li>Hands-on coding of Python and C++ based control systems for our instruments </li><li>Architecture and system design of next generation instruments </li><li>Long-term evolution of our instrument codebase </li><li>Mentoring of team members </li></ul>Minimum requirements <ul> <li>Bachelor's degree in computer science, engineering, math, or scientific discipline with 8 years experience; OR Master's degree with 6 years of experience in software development </li><li>Experience leading software team(s) in a technical capacity </li><li>Instrumentation system design & architecture </li><li>Modern C++ </li><li>Embedded Development </li><li>Python3 </li><li>Linux </li></ul>Preferred skills and experience <ul> <li>Control Systems Development </li><li>Firmware Development & EE knowledge (Digital & Analog Design) </li><li>Rapid software prototyping & validation with attention to detail and engineering diligence </li><li>Strong analytical and problem-solving skills </li><li>Strong verbal and written communication skills </li><li>Background in biology and DNA sequencing is not required. Interest in the field is. </li></ul> #LI-RT1 #LI-Onsite Below is the base pay range for this full time position. The actual base pay will depend on several factors unique to each candidate, including one's skills, qualifications, and experience. At 10x, base pay is also just one component of the Company's total compensation package. This role is also eligible for 10x's equity grants, its comprehensive health and retirement benefit programs, and its annual bonus program or sales incentive program. Your 10x recruiter can share more about the Company's total compensation package during the hiring process. Pay Range $203,000-$275,000 USD About 10x Genomics At 10x Genomics, accelerating our understanding of biology is more than a mission for us. It is a commitment. This is the century of biology, and the breakthroughs we make now have the potential to change the world. We enable scientists to advance their research, allowing them to address scientific questions they did not even know they could ask. Our tools have enabled fundamental discoveries across biology including cancer, immunology, and neuroscience. Our teams are empowered and encouraged to follow their passions, pursue new ideas, and perform at their best in an inclusive and dynamic environment. We know that behind every scientific breakthrough, there is a deep infrastructure of talented people driving the life sciences industry and making it possible for scientists and clinicians to make new strides. We are dedicated to finding the very best person for every aspect of our work because the innovations and discoveries that we enable together will lead to better technologies, better treatments, and a better future. Find out how you can make a 10x difference. Individuals seeking employment at 10x Genomics are considered without regards to race, color, religion, national origin, age, sex, marital status, ancestry, physical or mental disability, veteran status, gender identity, or sexual orientation, or any other characteristic protected by applicable law. 10x does not accept unsolicited applicants submitted by third-party recruiters or agencies. Any resume or application submitted to 10x without a vendor agreement in place will be considered unsolicited and property of 10x, and 10x will not pay a placement fee.

About the role We are looking for an exceptional Software Engineer to build out our growing cloud infrastructure and HPC platform with a solid understanding of Linux, cloud, and distributed computing to join our team. Our multi-disciplinary team in microfluidics, biochemistry, mechanical engineering, computational biology, and software has a proven track record of delivering successful commercial products built on deep technological innovation. If you are a self-starter who is passionate about building and operating reliable, scalable and performant systems, and is excited to work in a highly collaborative environment alongside a diverse team of experts every day, join us at 10x Genomics. This is a hybrid role in Pleasanton, CA. What you will be doing Design, build, deploy, and maintain resilient and scalable services and High Performance Computing (HPC) systems in the cloud. Scale systems and improve operational efficiency through extensive automation. Collaborate with the software engineering team on continuous delivery and deployment. Monitor infrastructure and applications for uptime and resource utilization, identify performance bottlenecks, troubleshoot and mitigate system issues, and develop solutions to improve reliability and performance. Maintain detailed documentation of system build and operational procedures. Participate in on-call rotations. Minimum Requirements Bachelor's degree in Computer Science or a related field, or equivalent work experience. 5 years software engineering experience in Python or Go. 3 years Linux systems engineering and operational experience. Experience with AWS services and infrastructure. Experience with Infrastructure as Code (ex. Terraform, Ansible), CI/CD tools/systems. Preferred Skills and Experience Proficiency in shell scripting and at least one other language, e.g. Python or Go. Ability to dive into unfamiliar code bases to troubleshoot and resolve issues. Previous experience with container based solutions like Docker. Experience with Kubernetes (installation, configuration, and troubleshooting). Knowledge of Linux kernel tuning, networking, and performance optimization. Experience with deployment management tools like ArgoCD. Experience in managing multi-petabyte scale network-attached storage (NAS) and operational knowledge of the NFS protocol. Strong desire to learn and implement new technologies. Excellent written and verbal communication skills. #LI-RW1 #LI-Onsite
Below is the base pay range for this full time position. The actual base pay will depend on several factors unique to each candidate, including one's skills, qualifications, and experience. At 10x, base pay is also just one component of the Company's total compensation package. This role is also eligible for 10x's equity grants, its comprehensive health and retirement benefit programs, and its annual bonus program or sales incentive program. Your 10x recruiter can share more about the Company's total compensation package during the hiring process.
Pay Range $177,000—$239,000 USD About 10x Genomics At 10x Genomics, accelerating our understanding of biology is more than a mission for us. It is a commitment. This is the century of biology, and the breakthroughs we make now have the potential to change the world. We enable scientists to advance their research, allowing them to address scientific questions they did not even know they could ask. Our tools have enabled fundamental discoveries across biology including cancer, immunology, and neuroscience. Our teams are empowered and encouraged to follow their passions, pursue new ideas, and perform at their best in an inclusive and dynamic environment. We know that behind every scientific breakthrough, there is a deep infrastructure of talented people driving the life sciences industry and making it possible for scientists and clinicians to make new strides. We are dedicated to finding the very best person for every aspect of our work because the innovations and discoveries that we enable together will lead to better technologies, better treatments, and a better future. Find out how you can make a 10x difference. Individuals seeking employment at 10x Genomics are considered without regards to race, color, religion, national origin, age, sex, marital status, ancestry, physical or mental disability, veteran status, gender identity, or sexual orientation,or any other characteristic protected by applicable law. 10x does not accept unsolicited applicants submitted by third-party recruiters or agencies. Any resume or application submitted to 10x without a vendor agreement in place will be considered unsolicited and property of 10x, and 10x will not pay a placement fee.

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