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10X Genomics Interview Questions

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You are testing hundreds of hypotheses with many t-tests. What considerations should be made?

What is a key disadvantage of the F-test when compared to multiple t-tests?

What is a key disadvantage of the F-test when compared to multiple t-tests?

Hundreds of Hypotheses

You are testing hundreds of hypotheses with many t-tests. What considerations should be made?

Let’s say that your company is running a standard control and variant AB test on a feature to increase conversion rates on the landing page. The PM checks the results and finds a .04 p-value.

How would you assess the validity of the result?

Experiment Validity

Suppose there exists a new airline named Jetco that flies domestically across North America. Jetco recently had a study commissioned that tested the boarding time of every airline, and it came out that Jetco had the fastest average boarding times of any airline.

What factors could have biased this result, and what would you look into?

What could potentially bias the average boarding time in favor of an airline that only flies domestically?

What could potentially bias the average boarding time in favor of an airline that only flies domestically?

Boarding Times Bias

A new airline came out as the fastest average boarding times compared to other airlines.  What factors could have biased this result and what would you look into?

10X Genomics Salaries by Position

About the role 10x Genomics creates powerful scientific tools that enable key biological discoveries and drive exponential progress in the study of human health. Our talented team has a distinguished record of creating innovative instruments, reagents, and software that analyze biological systems at a resolution that matches the complexity of biology. Scientists have used our tools to discover the mechanisms behind Alzheimer's disease, cystic fibrosis, autism, stem cell differentiation, COVID-19, and more. You will be working on modern React-powered applications, incorporating modern front-end development techniques with the cutting edge of biology. You will build best-in-class experiences on the web for customers to discover, explore, and purchase the entire 10x Genomics product line. If you are the kind of person who is an avid fan of technology in all fields, not just your own, and want to apply your talent alongside a diverse team of experts every day, join us at 10x Genomics. What you will be doing <ul><li>Designing, building, testing, and shipping production-ready software. </li> <li>Developing interactive web based applications. </li> <li>Collaborating with designers to create flexible, attractive visual components. </li> <li>Creating pages and workflows in scientifically-focused software applications. </li> </ul> Minimum Requirements <ul><li>Bachelor's degree in computer science, engineering, math, or scientific discipline AND6 years of software development experience; OR 8 years of professional experience building software. </li> <li>3 years of experience building web applications in React. </li> </ul> Preferred skills and experience <ul><li>Experience testing and deploying applications to the web. </li> <li>Knowledge of modern Javascript syntax and CSS features. </li> <li>Familiarity with TypeScript. </li> <li>Familiarity with Postgres or other modern relational databases. </li> <li>Experience building and maintaining RESTful APIs </li> <li>Willingness to solve problems irrespective of where it is in the tech stack. </li> <li>A background in biology is not required, but curiosity and scientific interest is. </li> </ul> #LI-RW1 #LI-Onsite Below is the U.S. base pay range for this full-time position. The actual base pay will depend on several factors unique to each candidate, including one's skills, qualifications, experience, and location. At 10x, base pay is also just one component of the Company's total compensation package. This role is also eligible for 10x's equity grants, its comprehensive health and retirement benefit programs, and its annual bonus program or sales incentive program. Your 10x recruiter can share more about the specific base pay range for your preferred location, as well as the Company's total compensation package, during the hiring process. Pay Range $173,000$275,000 USD About 10x Genomics At 10x Genomics, accelerating our understanding of biology is more than a mission for us. It is a commitment. This is the century of biology, and the breakthroughs we make now have the potential to change the world. We enable scientists to advance their research, allowing them to address scientific questions they did not even know they could ask. Our tools have enabled fundamental discoveries across biology including cancer, immunology, and neuroscience. Our teams are empowered and encouraged to follow their passions, pursue new ideas, and perform at their best in an inclusive and dynamic environment. We know that behind every scientific breakthrough, there is a deep infrastructure of talented people driving the life sciences industry and making it possible for scientists and clinicians to make new strides. We are dedicated to finding the very best person for every aspect of our work because the innovations and discoveries that we enable together will lead to better technologies, better treatments, and a better future. Find out how you can make a 10x difference. Individuals seeking employment at 10x Genomics are considered without regards to race, color, religion, national origin, age, sex, marital status, ancestry, physical or mental disability, veteran status, gender identity, or sexual orientation,or any other characteristic protected by applicable law. 10x does not accept unsolicited applicants submitted by third-party recruiters or agencies. Any resume or application submitted to 10x without a vendor agreement in place will be considered unsolicited and property of 10x, and 10x will not pay a placement fee.

About the role:
We are seeking an outstanding Sr. Manager, Plastics New Product Introduction (pNPI) to join the Manufacturing Systems Engineering (MSE) team at 10x Genomics. This individual will play a pivotal leadership role within the Global Operations Engineering team. This multi-disciplinary position involves close collaboration with various groups including Microfluidics, Supply Chain Management, New Product Development, Product Service and Support, and Instrument Lifecycle Engineering. You will lead a team of engineers and technicians responsible for transferring new plastic components to volume manufacturing. This role partners with the Operations, NPI, Customer Support, and R&D teams to improve robustness and efficiencies across multiple product lines.
The ideal candidate will have a proven track record in supporting complex plastic components used in on-market equipment for the life science or medical device industry. They should possess a broad understanding of the design and manufacturing of complex plastic systems and excel in solving complex problems. As a member of the team, you will be instrumental in supporting 10x manufacturing, supply chain, and service & support teams to deliver products that enable accelerated understanding of biology.
What you will be doing:
<ul>
<li>Lead a team responsible for the release to volume manufacturing of complex plastic consumables, including LSR-thermoplastic assemblies, COC/COP precision molded microfluidics consumables, and related plastic components.</li>
<li>Sustain and enhance on-market products for reliability, yield, vendor quality, continuity of supply, and part obsolescence.</li>
<li>Direct the transfer of new parts to suppliers utilizing compounding, molding, solvent bonding of thermoplastics and elastomers, COC, COP, and LSR.</li>
<li>Build, coach, and lead a diverse team of engineers and technicians.</li>
<li>Organize and manage projects to improve costs and product yield, ensuring smooth production transfer of new designs to established volume manufacturers.</li>
<li>Identify opportunities for enhancing supplier quality and internal systems; implement process improvements driven by Six Sigma and Lean methodologies to achieve continuous improvement in on-market products.</li>
<li>Utilize Arena PLM and Oracle ERP systems to manage product lifecycle and manufacturing processes effectively.</li>
<li>Conduct occasional supplier visits to support quality audits and new vendor capability assessments.</li>
<li>Ensure close collaboration with microfluidics and pNPI teams.</li>
<li>Act swiftly across the organization to build consensus and take rapid action to address field issues.</li>
<li>Drive the team to achieve short- and long-term goals for new product launches.</li>
<li>Develop and advocate for plastics development strategies that support R&D and manufacturing needs.</li>
<li>Drive innovation and continuous improvement in a fast-paced, dynamic environment.</li>
</ul>

Minimum Requirements:
<ul>
<li>BS in Mechanical, Plastics, or Manufacturing Engineering.</li>
<li>At least 7+ years of experience, preferably within biotechnology or life science engineering or manufacturing.</li>
<li>Experience with structured problem-solving methods and proficiency in using large data sets to drive decisions.</li>
<li>Familiarity with Six Sigma and Lean methodologies; Six Sigma Green/Black Belt certification is desired.</li>
<li>Experience with Arena PLM and Oracle ERP systems.</li>
<li>Ability to travel internationally as needed.</li>
<li>Ability to perform under pressure and adapt to changes (e.g., priorities and timelines).</li>
<li>Strong written and oral communication skills.</li>
</ul>


Preferred Skills and Experience:
<ul>
<li>PhD/MS in Polymer Science, Material Science, Mechanical Engineering, or equivalent.</li>
<li>A minimum of 10 years of industrial experience in plastics consumables, including DfM/DfX, formulations, compounding, molding, testing, co-molding, and SLR overmolding.</li>
<li>Familiarity with statistical data analysis tools and design of experiments.</li>
<li>Proven ability to lead a plastics application development team.</li>
<li>Direct experience with plastics injection molding process optimization and process transfer.</li>
</ul>


#LI-MH1 #on-site Below is the base pay range for this full time position. The actual base pay will depend on several factors unique to each candidate, including one's skills, qualifications, and experience. At 10x, base pay is also just one component of the Company's total compensation package. This role is also eligible for 10x's equity grants, its comprehensive health and retirement benefit programs, and its annual bonus program or sales incentive program. Your 10x recruiter can share more about the Company's total compensation package during the hiring process. Pay Range $171,000—$231,000 USD About 10x Genomics
At 10x Genomics, accelerating our understanding of biology is more than a mission for us. It is a commitment. This is the century of biology, and the breakthroughs we make now have the potential to change the world. We enable scientists to advance their research, allowing them to address scientific questions they did not even know they could ask. Our tools have enabled fundamental discoveries across biology including cancer, immunology, and neuroscience. Our teams are empowered and encouraged to follow their passions, pursue new ideas, and perform at their best in an inclusive and dynamic environment. We know that behind every scientific breakthrough, there is a deep infrastructure of talented people driving the life sciences industry and making it possible for scientists and clinicians to make new strides. We are dedicated to finding the very best person for every aspect of our work because the innovations and discoveries that we enable together will lead to better technologies, better treatments, and a better future. Find out how you can make a 10x difference.
Individuals seeking employment at 10x Genomics are considered without regards to race, color, religion, national origin, age, sex, marital status, ancestry, physical or mental disability, veteran status, gender identity, or sexual orientation,or any other characteristic protected by applicable law.
10x does not accept unsolicited applicants submitted by third-party recruiters or agencies. Any resume or application submitted to 10x without a vendor agreement in place will be considered unsolicited and property of 10x, and 10x will not pay a placement fee.

About the Role:
We are seeking a Staff Product Manager, Instrumentation to lead the commercial efforts of our single cell instrumentation line. This position will report to the Director of Product Management, Single Cell, and will be responsible for a) leading the execution of product management activities for workflow automation, ensuring the right product concept, fit, requirements, and eventual launch of product(s), and b) leading instrument life cycle management efforts for the Chromium portfolio. This role will require deep collaboration with multiple stakeholders within the single cell product portfolio and marketing program management, marketing communications, sales, support, R&D, and operations teams. They will be responsible for owning the business case, financial assumptions and pricing, positioning, and portfolio fit for the single cell instrument product lines.
What you will be doing:
Defines and maintains business plan for single cell instrumentation (benchtop and automation), including developing an integrated instrument strategy and roadmap and sustaining projects to drive improvements.
Interfaces with sales and customers regularly to characterize market needs and gaps, opportunities and trends, competitive and technology landscape for the single cell platform.
Serves as primary customer advocate during product development and sustaining projects to regularly evaluate feature requests and product enhancements; drives tradeoff decisions.
Works closely with manufacturing operations, quality, and support on product issues to ensure products meet customer expectations.
Collaborates with Regional Marketing, Global Marketing counterparts and Business Development to support marketing and sales enablement activities, as well activities related to strategic 3rd party partnerships.
Marketing lead for the instrument life cycle management team, defining prioritization, scope, and resourcing of sustaining projects for single cell instrumentation.
Educates sales and regional marketing on the single cell product line positioning and specifications.
Designs / implements effective market and forecast models for single cell instrumentation with stakeholders to provide granularity at the regional, market, and segment level.
Sets pricing strategy and monitors key performance indicators to ensure single cell instrument portfolio delivers against product profitability goals.
Minimum Qualifications:
BS in life science field - with experience in NGS methods.
6 years of experience in product management or marketing in Life Sciences or Clinical industry.
Strong technical knowledge of genomics, and/or next generation sequencing and molecular biology products.
Experience in hardware product management required including product launch.
Must have experience in customer interactions in either a Sales, Support, or Marketing function.
Must have experience creating financial models and business cases; strong Excel skills.
Experience conducting market research and developing detailed product requirements.
Demonstrated ability to develop long-term product strategies and go-to-market plans.
Must have proficient written, communication and presentation skills with the ability to present to diverse audiences.
Experience working in highly technical and cross-functional teams covering various internal organizations.
Ability to influence across the organization at all levels.
Exceptional time and project management skills and ability to prioritize competing requests.
Self-starter willing to work in a fast-paced environment.
Must be willing to travel up to 30%.
Preferred Skills/Qualifications:
PhD or advanced degree preferred.
About 10x Genomics
At 10x Genomics, accelerating our understanding of biology is more than a mission for us. It is a commitment. This is the century of biology, and the breakthroughs we make now have the potential to change the world. We enable scientists to advance their research, allowing them to address scientific questions they did not even know they could ask. Our tools have enabled fundamental discoveries across biology including cancer, immunology, and neuroscience. Our teams are empowered and encouraged to follow their passions, pursue new ideas, and perform at their best in an inclusive and dynamic environment. We know that behind every scientific breakthrough, there is a deep infrastructure of talented people driving the life sciences industry and making it possible for scientists and clinicians to make new strides. We are dedicated to finding the very best person for every aspect of our work because the innovations and discoveries that we enable together will lead to better technologies, better treatments, and a better future. Find out how you can make a 10x difference.
Individuals seeking employment at 10x Genomics are considered without regards to race, color, religion, national origin, age, sex, marital status, ancestry, physical or mental disability, veteran status, gender identity, or sexual orientation, or any other characteristic protected by applicable law.

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10X Genomics Interview Questions

10X Genomics Interview Guides

10X Genomics Interview Questions

10X Genomics Salaries by Position

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