The University of Iowa Hospitals and Clinics department of Radiology is seeking a a full-time Assistant Research Scientist within the Radiology Department. The primary function of this position is to develop innovative pulse sequence and image reconstruction methods and analyze quantitative MR imaging for the assessment of neurological disorders within the MR Research Facility. This will include the development of new MR elastography as well as imaging techniques that are sensitive to brain tissue damage and alterations in biomechanical property. This will include the development of analysis tools to generate quantitative results from the acquired data. In addition, this position will report the results from these efforts in scientific publications as well as support the writing and submission of grant applications.The incumbent is expected to work in a fast-paced research environment with diverse team of investigators, students, and staff members. In addition, the incumbent will work with state-of-the-art imaging equipment including research dedicated 3T, 7T whole body and brain only scanners and a small animal 7T scanner.Position ResponsibilitiesExperiments, Simulation, Modeling or Theoretical Investigation:* Identify and define problems, solutions to which can be approached through a scientific research process.* Design and execute experiments* Work independently on basic research tasks with oversight by Faculty or Principal Investigator (PI).* Contribute to documentation of equipment and procedures.Data/Research Analysis and Evaluation* Collect and perform statistical data analysis. Evaluate data to establish relevance to the problem or problems being investigated.* Perform basic data analysis techniques.* Compare results of scientific investigations to previously published work.Dissemination of research results* Prepare research results for publication in reports, papers, journals, books, grants and other media.* Present results in in departmental seminars and professional meetings.Research Proposal/Grants:* Develop new grant proposals for research and obtain support for new and/or continuing research activities.* Maintain liaison with sponsoring agencies and organizations as well as with other research and educational institutions.* Participate in determining research priorities and planning programs of research.* Contribute to progress reports required by funding agencies.Services:* Provide service to the scientific community, University and General Public.* Review Submitted manuscripts and research proposals.* Consult and collaborate with research community.* May participate in national and international meetings within discipline.Human Resources/Supervision:* Mentor graduate students.* May provide functional and/or administrative supervision for staff.* Provide direction, assignments, feedback, coaching and counseling to assure outcomes are achieved.TECHNICAL COMPETENCIESQuantitative Research:Knowledge of and the ability to use numerical methods to compile information about a given situation or condition.Research Analysis:Knowledge of and the ability to locate, interpret and evaluate research findings compiled and documented by others and use this material to support empirical research.Research Documentation:Knowledge of and the ability to utilize tools and techniques for producing well-written, meaningful and usable documentation of research findings.Research Ethics/Compliance:Knowledge of practices, behaviors, applicable laws, rules and regulations governing proper research conduct. Ability to demonstrate ethical and compliant behavior in diverse situations.Research Safety:Knowledge of the procedures and programs in place in the organization to ensure employee, student and subject safety (occupational safety, fire, patient, animal, drug, radiation, environmental safety and emergency plans). Ability to take appropriate action in case of emergency.SUPERVISION RECEIVEDSupervision is received from the MRI Recharge Center, Xi Peng, PhDSUPERVISION EXERCISEDFunctional supervision may be exercised over support staff and studentsPay Grade: 5APay Structure A: https://hr.uiowa.edu/pay/pay-plans/professional-and-scientific-pay-structureBenefits Highlights:* Regular salaried position located in Iowa City, Iowa* Fringe benefit package including paid vacation; sick leave; health, dental, life and disability insurance options; and generous employer contributions into retirement plans* For more information about Why Iowa?, click hereREQUIRED QUALIFICATIONS* A Ph.D. in an engineering or science field such as Medical Physics, Biomedical Engineering, Electrical Engineering, Chemistry, or Computer Science is required.* Training in MR imaging, medical imaging or related scientific discipline is required.* Excellent verbal and written communication skills are required.* Demonstrated strong analytical and data analysis skills are required.* Experience with MRI pulse sequence development is required.* Experience with MR image reconstruction is required.* Experience with MR data analysis is required.* Experience with Python is required.DESIRED QUALIFICATIONS* Prior postdoctoral training in MR imaging/elastography is highly desired* Prior research experience in MR elastography or MR imaging (e.g. quantitative imaging) sensitive to brain tissue damage and malformation highly desired.* Prior success with grant applications and peer-reviewed publications is highly desired.* Knowledge of GE EPIC pulse programming environment is desired* Prior experience with ultra-high field MR imaging and spectroscopy is desired.* Development experience in medical image analysis of different imaging modalities (e.g. MRI ) is desired.Application Process: In order to be considered, applicants must upload Cover Letter and Resume (under submission relevant materials) that clearly address how they meet the listed required and desired qualifications of this position.Job openings are posted for a minimum of 14 calendar days.Successful candidates will be required to self-disclose any conviction history and will be subject to a criminal background check and credential/education verification.For additional questions or concerns, please reach out to Xi Peng at xi-peng@uiowa.edu.Additional Information* Classification Title: Asst Research Scientist/Engin* Appointment Type: Professional and Scientific* Schedule: Full-time* Work Modality Options: On CampusCompensation* Pay Level: 5AContact Information* Organization: Healthcare* Contact Name: Xi Peng* Contact Email: xi-peng@uiowa.edu

BASIC FUNCTION AND RESPONSIBILITY This person will work in the research laboratory of Dr. Maria Spies on the structural (CryoEM and X-ray crystallography) studies of the molecular machines maintaining human genome stability, and on structure-based drug discovery. This person will be responsible for the generation and interpretation of experimental data, presentation of the data at scientific meetings, drafting the scientific manuscripts describing the data and assisting in the daily operations of the laboratory. This person will be also encouraged to apply for extramural and/or intramural funding. CHARACTERISTIC DUTIES AND RESPONSIBILITIES <ul><li>Purification of DNA repair proteins RAD51, RAD52, RDM1, RPAs, PARP1, DNA helicases, etc. for structural and biophysical analysis, and for small molecule drug discovery.</li><li>Analysis of the nucleoprotein complexes by CryoEM and X-ray crystallography (sample and greed preparation, screen, data collection and data analysis).</li><li>Writing proposals for time on the CryoEM instruments at national facilities.</li><li>Teaching junior lab members in using biochemical and structural techniques.</li><li>Perform library research on topics studied, prepare research materials for reports, and assist in the preparation of papers for publication. </li><li>Present the data at regional, national and/or international meetings.</li><li>Order general laboratory supplies, maintain equipment, and sustain laboratory organization.</li><li>Analyze and interpret data with the help of others in the laboratory, and determine the validity of the results. Keep detailed laboratory notebooks recording experimental data and analyses and present these findings at weekly lab meetings. Recommend further experiments and/or changes in procedures.</li><li>Other duties as assigned.</li></ul> SUPERVISION RECEIVED Functional supervision is received from the Principal Investigator. WE CARE CORE VALUES <ul><li>Welcoming - We strive for an environment where everyone has a voice that is heard, that promotes the dignity of our patients, trainees, and employees, and allows all to thrive in their health, work, research, and education.</li><li>Excellence - We aim to achieve and deliver our personal and collective best in the pursuit of quality and accessible healthcare, education, and research.</li><li>Collaboration - We encourage collaboration with healthcare systems, providers, and communities across Iowa and the region, as well as within our UI community. We believe teamwork - guided by compassion - is the best way to work.</li><li>Accountability - We behave ethically, act with fairness and integrity, take responsibility for our own actions, and respond when errors in behavior or judgment occur.</li><li>Respect - We are committed to ensuring that UI Health Care is an inclusive environment where individuals from the full spectrum of diversity - which includes identity, backgrounds, cultures, ability and perspective -feel safe, seen, and valued.</li><li>Equity - We dedicate ourselves to equity and fairness in research, health care, education and health.</li></ul> Department Summary: For additional information about the Department of Biochemistry and Molecular Biology at the University of Iowa, please visit our website at: https://medicine.uiowa.edu/biochemistry. BASIC QUALIFICATIONS PhD in chemistry, biochemistry, structural biology, or related scientific discipline. Prior postdoctoral experience. Strong publication record. Expertise in CryoEM, X-ray crystallography and biochemical analysis of protein-DNA interactions, fluorescence spectroscopy, and HTS. Experience in purifying and working with human DNA repair proteins. Proficiency with Linux and PC. EXPERIENCE REQUIRED 1. Structural and biochemical analysis of protein-DNA interactions 2.CryoEM sample preparation, data collection and model building 3.Experience in purifying and working with human DNA repair proteins. 4.Proficiency in computer use (Windows and Office applications, GraphPad Prism, contemporary CryoEM and X-ray crystallography software). 5. Demonstrated excellent written and verbal communication skills DESIRABLE QUALIFICATIONS 1. Strong organizational skills 2. Knowledge of the fundamental mechanisms of homologous recombination, DNA repair, DNA replication, genome stability 3. Experience with bacterial and mammalian cell culture POSITION AND APPLICATION DETAILS To be considered, applicants must upload the following documents and mark them as "Relevant File" to the submission: <ul><li>Resume</li><li>Cover Letter</li></ul> Job openings are posted for a minimum of 14 calendar days and may be removed from posting and filled any time after the original posting period has ended. Successful candidates will be required to self-disclose any conviction history and will be subject to a criminal background check and credential/education verification. Up to 5 professional references will be requested at a later step in the recruitment process. This position is not eligible for University sponsorship for employment authorization. For additional questions, please contact Rosemary Stratton at rosemary-stratton@uiowa.edu.

The University of Iowa Hospitals and Clinics department of Radiology is seeking a a full-time Assistant Research Scientist within the Radiology Department. The primary function of this position is to develop innovative pulse sequence and image recons Research Scientist, Radiology, Research, Assistant, Scientist, Imaging, Technology, Education

BASIC FUNCTION AND RESPONSIBILITYThis person will work in the research laboratory of Dr. Maria Spies on the structural (CryoEM and X-ray crystallography) studies of the molecular machines maintaining human genome stability, and on structure-based drug discovery. This person will be responsible for the generation and interpretation of experimental data, presentation of the data at scientific meetings, drafting the scientific manuscripts describing the data and assisting in the daily operations of the laboratory. This person will be also encouraged to apply for extramural and/or intramural funding.CHARACTERISTIC DUTIES AND RESPONSIBILITIES* Purification of DNA repair proteins RAD51, RAD52, RDM1, RPAs, PARP1, DNA helicases, etc. for structural and biophysical analysis, and for small molecule drug discovery.* Analysis of the nucleoprotein complexes by CryoEM and X-ray crystallography (sample and greed preparation, screen, data collection and data analysis).* Writing proposals for time on the CryoEM instruments at national facilities.* Teaching junior lab members in using biochemical and structural techniques.* Perform library research on topics studied, prepare research materials for reports, and assist in the preparation of papers for publication.* Present the data at regional, national and/or international meetings.* Order general laboratory supplies, maintain equipment, and sustain laboratory organization.* Analyze and interpret data with the help of others in the laboratory, and determine the validity of the results. Keep detailed laboratory notebooks recording experimental data and analyses and present these findings at weekly lab meetings. Recommend further experiments and/or changes in procedures.* Other duties as assigned.SUPERVISION RECEIVEDFunctional supervision is received from the Principal Investigator.WE CARE CORE VALUES* Welcoming - We strive for an environment where everyone has a voice that is heard, that promotes the dignity of our patients, trainees, and employees, and allows all to thrive in their health, work, research, and education.* Excellence - We aim to achieve and deliver our personal and collective best in the pursuit of quality and accessible healthcare, education, and research.* Collaboration - We encourage collaboration with healthcare systems, providers, and communities across Iowa and the region, as well as within our UI community. We believe teamwork - guided by compassion - is the best way to work.* Accountability - We behave ethically, act with fairness and integrity, take responsibility for our own actions, and respond when errors in behavior or judgment occur.* Respect - We are committed to ensuring that UI Health Care is an inclusive environment where individuals from the full spectrum of diversity - which includes identity, backgrounds, cultures, ability and perspective -feel safe, seen, and valued.* Equity - We dedicate ourselves to equity and fairness in research, health care, education and health.Department Summary: For additional information about the Department of Biochemistry and Molecular Biology at the University of Iowa, please visit our website at: https://medicine.uiowa.edu/biochemistry.BASIC QUALIFICATIONSPhD in chemistry, biochemistry, structural biology, or related scientific discipline. Prior postdoctoral experience. Strong publication record. Expertise in CryoEM, X-ray crystallography and biochemical analysis of protein-DNA interactions, fluorescence spectroscopy, and HTS. Experience in purifying and working with human DNA repair proteins. Proficiency with Linux and PC.EXPERIENCE REQUIRED1. Structural and biochemical analysis of protein-DNA interactions2. CryoEM sample preparation, data collection and model building3. Experience in purifying and working with human DNA repair proteins.4. Proficiency in computer use (Windows and Office applications, GraphPad Prism, contemporary CryoEM and X-ray crystallography software).5. Demonstrated excellent written and verbal communication skillsDESIRABLE QUALIFICATIONS1. Strong organizational skills2. Knowledge of the fundamental mechanisms of homologous recombination, DNA repair, DNA replication, genome stability3. Experience with bacterial and mammalian cell culturePOSITION AND APPLICATION DETAILSTo be considered, applicants must upload the following documents and mark them as "Relevant File" to the submission:* Resume* Cover LetterJob openings are posted for a minimum of 14 calendar days and may be removed from posting and filled any time after the original posting period has ended.Successful candidates will be required to self-disclose any conviction history and will be subject to a criminal background check and credential/education verification. Up to 5 professional references will be requested at a later step in the recruitment process. This position is not eligible for University sponsorship for employment authorization.For additional questions, please contact Rosemary Stratton at rosemary-stratton@uiowa.edu.Additional Information* Classification Title: Asst Research Scientist/Engin* Appointment Type: Professional and Scientific* Schedule: Full-time* Work Modality Options: On CampusCompensation* Pay Level: PRJ1Contact Information* Organization: Healthcare* Contact Name: Rosemary Stratton* Contact Email: rosemary-stratton@uiowa.edu

For additional information about the Department of Biochemistry and Molecular Biology at the University of Iowa, please visit our website at: BASIC QUALIFICATIONS PhD in chemistry, biochemistry, structural biology, or related scientific discipline. P Research Scientist, Chemistry, Biology, Biochemist, Chemist, Assistant, Technology, Education

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Research Scientist Jobs in Iowa City, IA

Assistant Research ScientistradiologyMay 26, 2024

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